The risk posed by the compelling desire to reduce or discontinue benzodiazepines is perhaps best illustrated by the following case vignette. Picture of diazepam to determine the effect of sedation using diazepam on hemoglobin oxygen saturation SpO in patients undergoing esophagogastroduodenoscopy EGD. Also, it is a more acceptable agent because of its oral route of picture of diazepam administration. One user of benzodiazepines told the Sunday Herald he had recently been given repeat prescriptions for eight months without having to see a doctor. Properly obtaining and effectively documenting informed consent. Of the 65 patients given IV diazepam, 31 patients had no prior intravenous access and 34 picture of diazepam patients had an intravenous access already present. Patients who already had an intravenous access present were treated with 0,2 mg,kg of intravenous diazepam for control of seizures and time interval from administration of diazepam to cessation of seizures was noted. It has Picture of diazepam been recognised that anticholinergic drugs may precipitate delirium. The drug has been shown to depress centrally elicited cardiovascular Picture of diazepam stimulation. An investigation by the Sunday Herald has revealed a shocking picture of the scale of use of powerful tranquillisers known as benzodiazepines. Out of the 5 grade IV cases, one case had a pulse rate of 116 per minute; this patient expired due to cardiorespiratory failure within 24 hours. The dose of diazepam varied Picture of diazepam from 20-240 mg daily in 4-6 divided doses. Diazepam is one of the most frequently used benzodiazepines both intravenously as well as picture of diazepam rectally. ”Once you start withdrawing it, the individual is going to start to experience conditions such as anxiety and difficulty sleeping – conditions for which the drug was prescribed in the first place, picture of diazepam he said. But there are still concerns surrounding overprescribing by medics. For the purpose of statistical comparison the severity of the disease was graded according to the criteria of Patel and Joag, except that the grades IV and V, were graded together as grade IV only as there were only a few cases in grade V. CONCLUSION, Intravenous diazepam administration before EGD produces a significant fall in SpO2 during the procedure, and so should be avoided; continuous monitoring of SpO2 should Picture of diazepam be done during EGD. The duration of suboptimal SpO2 was similar means, – SD being 2,47, 0,10 min in diazepam group and 2,86, 0,32 min in placebo group.